Record Information
Version1.0
Creation date2018-05-02 12:46:30 UTC
Update date2018-05-04 14:15:24 UTC
FoodComEx IDPC001212
FoodDB RecordFDB023808
Chemical Information
NameN-Acetylglutamine
DescriptionN-Acetylglutamine (GIcNAc) is a modified amino acid (an acetylated analogue of glutamine), a metabolite present in normal human urine. The decomposition products of GIcNAc have been identified by NMR and HPLC-MS as N-acetyl-L-glutamic acid, N-(2,6-dioxo-3-piperidinyl) acetamide, pyroglutamic acid, glutamic acid, and glutamine. GIcNAc is used for parenteral nutrition as a source of glutamine, since glutamine is too unstable, but GIcNAc is very stable. In patients treated with aminoglycosides and/or glycopeptides, elevation GIcNAc in urine suggests renal tubular injury. High amounts of N-acetylated amino acids (i.e.: N-Acetylglutamine) were detected patient with aminoacylase I deficiency (EC 3.5.1.14, a homodimeric zinc-binding metalloenzyme located in the cytosol), a novel inborn error of metabolism. (PMID: 15331932, 11312773, 7952062, 2569664, 16274666) [HMDB]
CAS Number2490-97-3
Structure
Thumb
Synonyms
SynonymSource
Aceglutamidhmdb
Aceglutamidehmdb
Acetylglutaminehmdb
alpha-n-acetyl-l-glutaminehmdb
L-2-Acetamidoglutaramic acidhmdb
L-N2-acetyl-Glutaminehmdb
N-acetyl-l-glutaminehmdb
N2-Acetyl-L-glutaminehmdb
N2-acetylglutaminehmdb
Chemical FormulaNot Available
IUPAC nameNot Available
InChI IdentifierInChI=1S/C7H12N2O4/c1-4(10)9-5(7(12)13)2-3-6(8)11/h5H,2-3H2,1H3,(H2,8,11)(H,9,10)(H,12,13)
InChI KeyKSMRODHGGIIXDV-UHFFFAOYSA-N
Isomeric SMILESCC(=O)NC(CCC(N)=O)C(O)=O
Average Molecular Weight188.1812
Monoisotopic Molecular Weight188.079706882
Chemical Taxonomy
ClassificationNot classified
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logPNot Available
Experimental Water SolubilityNot Available
Melting PointNot Available
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity Available1 to 2 mg
Delivery Time2 weeks
Storage Formpowder
Storage Conditions-18°C
StabilityNot Available
Purityunknown
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Augustin ScalbertInternational Agency for Research on Cancer (IARC), Biomarkers Group, 150 cours Albert Thomas, Lyon, FR, 69372scalberta@iarc.fr
Commercial Vendors
AKSci 4390AB
AKSci G131
AKSci J90788
MetaSci HMDB0006029
Sigma-Aldrich HMDB0006029