Record Information
Version1.0
Creation date2018-05-02 12:11:20 UTC
Update date2018-05-04 14:23:54 UTC
FoodComEx IDPC001182
FoodDB RecordFDB006725
Chemical Information
NameDimethyl sulfone
DescriptionDimethyl sulfone (DMSO2), also known as sulfonylbismethane, belongs to the class of organic compounds known as sulfones. Sulfones are compounds containing a sulfonyl group, with the general structure RS(=O)2R' (R,R' =alkyl, aryl). It occurs naturally in some primitive plants and is present in small amounts in many foods and beverages and it is marketed as a dietary supplement. This colorless solid features a sulfonyl functional group and is considered relatively inert chemically. Dimethyl sulfone reflects its close chemical relationship to dimethyl sulfoxide (DMSO), which differs only in the oxidation state of the sulfur atom. Dimethyl sulfone is the primary metabolite of DMSO in humans, and it shares some of the properties of DMSO. Dimethyl sulfone is a metabolite occurring in plasma and cerebrospinal fluid of normal humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism (PMID: 15996001). It is sometimes used as a cutting agent for illicitly manufactured methamphetamine. Because of its polarity and thermal stability, Dimethyl sulfone is used industrially as a high-temperature solvent for both inorganic and organic substances. Dimethyl sulfone is also commonly found in the atmosphere above marine areas, where it is used as a carbon source by the airborne bacteria Afipia (PMID: 23359712).
CAS Number67-71-0
Structure
Thumb
Synonyms
SynonymSource
(Methylsulfonyl)methaneHMDB
Dimethyl sulfonebiospider
Dimethyl sulphonebiospider
Dimethylsulfonebiospider
DMSO2manual
Lignisul msmHMDB
Methane, 1,1'-sulfonylbis-biospider
Methane, sulfonylbis-biospider
Methyl sulfonebiospider
Methylsulfonyl methanebiospider
Methylsulfonylmethanebiospider
MethylsulphonylmethaneGenerator
MSMbiospider
Opti msmHMDB
Sulfone, dimethyl-biospider
Sulfonylbis-methaneHMDB
Sulfonylbismethanebiospider
Sulfonyldimethanebiospider
Sulphonylbismethanebiospider
Chemical FormulaC2H6O2S
IUPAC namemethanesulfonylmethane
InChI IdentifierInChI=1S/C2H6O2S/c1-5(2,3)4/h1-2H3
InChI KeyHHVIBTZHLRERCL-UHFFFAOYSA-N
Isomeric SMILESCS(C)(=O)=O
Average Molecular Weight94.133
Monoisotopic Molecular Weight94.008850126
Chemical Taxonomy
Description Belongs to the class of organic compounds known as sulfones. Sulfones are compounds containing a sulfonyl group( which as the general structure RS(=O)2R' (R,R' =alkyl, aryl)) attached to two carbon atoms.
KingdomOrganic compounds
Super ClassOrganosulfur compounds
ClassSulfonyls
Sub ClassSulfones
Direct ParentSulfones
Alternative Parents
Substituents
  • Sulfone
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logP-1.41HANSCH,C ET AL. (1995)
Experimental Water SolubilityNot Available
Melting Point109 oC
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity Available1 to 2 mg
Delivery Time2 weeks
Storage Formpowder
Storage Conditions-18°C
StabilityNot Available
Purityunknown
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Augustin ScalbertInternational Agency for Research on Cancer (IARC), Biomarkers Group, 150 cours Albert Thomas, Lyon, FR, 69372scalberta@iarc.fr
Commercial Vendors
AKSci Y5828
MetaSci HMDB0004983
Sigma-Aldrich HMDB0004983
Toronto Research Chemicals D479350