FComEx: Suberylglycine (PC000991)

Record Information

Version

1.0

Creation date

2015-10-09 22:33:41 UTC

Update date

2017-01-19 02:36:43 UTC

FoodComEx ID

PC000991

FoodDB Record

FDB022336

Chemical Information

Name

Suberylglycine

Description

Suberylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine Suberylglycine is a dicarboxylic acid. It is formed by glycine-N-acylase catalyzed conjugation (PMID 947635). It can be used for the diagnosis of hereditary medium-chain acyl-CoA dehydrogenase deficiency (PMID 2775902). [HMDB]

CAS Number

60317-54-6

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
Suberylglycin	hmdb
Suberylglycine	hmdb

Chemical Formula

C10H17NO5

IUPAC name

7-[(carboxymethyl)carbamoyl]heptanoic acid

InChI Identifier

InChI=1S/C10H17NO5/c12-8(11-7-10(15)16)5-3-1-2-4-6-9(13)14/h1-7H2,(H,11,12)(H,13,14)(H,15,16)

InChI Key

HXATVKDSYDWTCX-UHFFFAOYSA-N

Isomeric SMILES

OC(=O)CCCCCCC(=O)NCC(O)=O

Average Molecular Weight

231.2457

Monoisotopic Molecular Weight

231.110672659

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as n-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

N-acyl-alpha amino acids

Alternative Parents