FComEx: Propionylglycine (PC000985)

Record Information

Version

1.0

Creation date

2015-10-09 22:33:40 UTC

Update date

2017-01-19 02:36:43 UTC

FoodComEx ID

PC000985

FoodDB Record

FDB022240

Chemical Information

Name

Propionylglycine

Description

Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction: acyl-CoA + glycine < -- > CoA + N-acylglycine The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase. (Disorders of propionate and methylmalonate metabolism. In The Metabolic and Molecular Bases of Inherited Disease). [HMDB]

CAS Number

21709-90-0

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
N-propionyl-Glycine	hmdb
N-Propionylglycine	hmdb
Propionylglycine	hmdb

Chemical Formula

C5H9NO3

IUPAC name

2-propanamidoacetic acid

InChI Identifier

InChI=1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9)

InChI Key

WOMAZEJKVZLLFE-UHFFFAOYSA-N

Isomeric SMILES

CCC(=O)NCC(O)=O

Average Molecular Weight

131.1299

Monoisotopic Molecular Weight

131.058243159

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as n-acyl-alpha amino acids. N-acyl-alpha amino acids are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom.

Kingdom

Organic compounds

Super Class

Organic acids and derivatives

Class

Carboxylic acids and derivatives

Sub Class

Amino acids, peptides, and analogues

Direct Parent

N-acyl-alpha amino acids

Alternative Parents