| Record Information |
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| Version | 1.0 |
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| Creation date | 2015-10-09 22:33:40 UTC |
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| Update date | 2017-01-19 02:36:43 UTC |
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| FoodComEx ID | PC000985 |
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| FoodDB Record | FDB022240 |
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| Chemical Information |
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| Name | Propionylglycine |
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| Description | Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:
acyl-CoA + glycine < -- > CoA + N-acylglycine
The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase. (Disorders of propionate and methylmalonate metabolism. In The Metabolic and Molecular Bases of Inherited Disease). [HMDB] |
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| CAS Number | 21709-90-0 |
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| Structure | |
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| Synonyms | | Synonym | Source |
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| N-propionyl-Glycine | hmdb | | N-Propionylglycine | hmdb | | Propionylglycine | hmdb |
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| Chemical Formula | C5H9NO3 |
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| IUPAC name | 2-propanamidoacetic acid |
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| InChI Identifier | InChI=1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9) |
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| InChI Key | WOMAZEJKVZLLFE-UHFFFAOYSA-N |
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| Isomeric SMILES | CCC(=O)NCC(O)=O |
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| Average Molecular Weight | 131.1299 |
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| Monoisotopic Molecular Weight | 131.058243159 |
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| Chemical Taxonomy |
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| Classification | Not classified |
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| Physico-Chemical Properties - Experimental |
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| Property | Value | Reference |
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| Experimental logP | Not Available | |
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| Experimental Water Solubility | Not Available | |
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| Melting Point | Not Available | |
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| Foods of Origin |
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| Food | Content Range | Average | Reference |
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| Food | | | Reference |
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| Production Data |
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| Production Method | commercial |
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| Production Method Reference | Not Available |
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| Production Method Reference File | Not Available |
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| Quantity Available | Production upon request, up to 50 mg |
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| Delivery Time | Not Available |
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| Storage Form | solid |
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| Storage Conditions | -80°C |
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| Stability | Not Available |
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| Purity | Not Available |
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| Spectra |
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| Spectral Data Upon Request | Not Available |
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| Provider Information |
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| Commercial Vendors |
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| AKSci | 7387AD |
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| Matrix Scientific | HMDB0000783 |
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| MetaSci | HMDB0000783 |
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| Toronto Research Chemicals | P788500 |
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