FComEx: 6-Hydroxynicotinic acid (PC000810)

Record Information

Version

1.0

Creation date

2015-10-09 22:32:51 UTC

Update date

2017-01-19 02:36:37 UTC

FoodComEx ID

PC000810

FoodDB Record

FDB023041

Chemical Information

Name

6-Hydroxynicotinic acid

Description

6-hydroxynicotinic acid (6-OHNA) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. Among the common bacteria causing urinary infection, only P. aeruginosa produces 6-hydroxynicotinic acid from nicotinic acid. Pseudomonas aeruginosa infection has been reported to be the third leading cause of urinary infection, accounting for 11% of such infections, the first and second being Escherichia coli and Klebsiella pneumonia, respectively. Analyses of the NMR spectra of the bacterial media with variable cell count of P. aeruginosa, shows that the intensity of the signals of the 6-hydroxynicotinic acid increases with increasing number of bacterial cells. (PMID: 3926801, 15759292) [HMDB]

CAS Number

5006-66-6

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
1,6-Dihydro-6-oxo-3-pyridinecarboxylic acid	hmdb
1,6-dihydro-6-oxo-Nicotinic acid	hmdb
2-Hydroxy-5-carboxypyridine	hmdb
2-Hydroxypyridine-5-carboxylic acid	hmdb
2-Pyridone-5-carboxylic acid	hmdb
5-Carboxy-2-pyridone	hmdb
6-hydroxy-Nicotinic acid	hmdb
6-Hydroxyniacin	hmdb
6-Hydroxynicotinate	hmdb
6-Hydroxynicotinic acid	hmdb
6-Hydroxypyridine-3-carboxylic acid	hmdb

Chemical Formula

C6H5NO3

IUPAC name

6-hydroxypyridine-3-carboxylic acid

InChI Identifier

InChI=1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)

InChI Key

BLHCMGRVFXRYRN-UHFFFAOYSA-N

Isomeric SMILES

OC(=O)C1=CN=C(O)C=C1

Average Molecular Weight

139.1088

Monoisotopic Molecular Weight

139.026943031

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pyridinecarboxylic acids. Pyridinecarboxylic acids are compounds containing a pyridine ring bearing a carboxylic acid group.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Pyridines and derivatives

Sub Class

Pyridinecarboxylic acids and derivatives

Direct Parent

Pyridinecarboxylic acids

Alternative Parents