| Record Information |
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| Version | 1.0 |
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| Creation date | 2015-10-09 22:32:46 UTC |
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| Update date | 2017-01-19 02:36:36 UTC |
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| FoodComEx ID | PC000802 |
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| FoodDB Record | FDB023822 |
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| Chemical Information |
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| Name | o-Tyrosine |
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| Description | o-Tyrosine is a normal human metabolite. Its presence is possible due to the hydroxylation of l-phenylalanine by hydroxyl radical (*OH), and is proposed as an hydroxy radical biomarker of oxidative damage to proteins. o-Tyrosine might also be included in the diet and absorbed. It has been associated with disease such as Kwashiorkor, a severe form of protein-energy malnutrition. However, many publications mention that the results are inconclusive, and o-tyrosine is not selectively altered by antioxidant intervention, exercise training or age. (PMID: 14670743, 10969271, 9887186) [HMDB] |
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| CAS Number | 2370-61-8 |
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| Structure | |
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| Synonyms | | Synonym | Source |
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| 2-hydroxy-DL-Phenylalanine | hmdb | | 2-hydroxy-Phenylalanine | hmdb | | 2-Hydroxyphenylalanine | hmdb | | 2-Tyrosine | hmdb | | 3-(o-hydroxyphenyl)DL-Alanine | hmdb | | DL- O-tyrosine | hmdb | | DL-3-(o-Hydroxyphenyl)alanine | hmdb | | DL-o-tyrosine | hmdb | | Ortho-tyrosine | hmdb |
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| Chemical Formula | C9H11NO3 |
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| IUPAC name | 2-amino-3-(2-hydroxyphenyl)propanoic acid |
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| InChI Identifier | InChI=1S/C9H11NO3/c10-7(9(12)13)5-6-3-1-2-4-8(6)11/h1-4,7,11H,5,10H2,(H,12,13) |
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| InChI Key | WRFPVMFCRNYQNR-UHFFFAOYSA-N |
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| Isomeric SMILES | NC(CC1=CC=CC=C1O)C(O)=O |
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| Average Molecular Weight | 181.1885 |
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| Monoisotopic Molecular Weight | 181.073893223 |
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| Chemical Taxonomy |
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| Description | Belongs to the class of organic compounds known as phenylalanine and derivatives. Phenylalanine and derivatives are compounds containing phenylalanine or a derivative thereof resulting from reaction of phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. |
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| Kingdom | Organic compounds |
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| Super Class | Organic acids and derivatives |
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| Class | Carboxylic acids and derivatives |
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| Sub Class | Amino acids, peptides, and analogues |
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| Direct Parent | Phenylalanine and derivatives |
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| Alternative Parents | |
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| Substituents | - Phenylalanine or derivatives
- 3-phenylpropanoic-acid
- Amphetamine or derivatives
- Alpha-amino acid
- 1-hydroxy-2-unsubstituted benzenoid
- 1-hydroxy-4-unsubstituted benzenoid
- Aralkylamine
- Phenol
- Monocyclic benzene moiety
- Benzenoid
- Amino acid
- Carboxylic acid
- Monocarboxylic acid or derivatives
- Organic oxygen compound
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Hydrocarbon derivative
- Primary aliphatic amine
- Organic nitrogen compound
- Carbonyl group
- Organic oxide
- Organopnictogen compound
- Amine
- Aromatic homomonocyclic compound
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| Molecular Framework | Aromatic homomonocyclic compounds |
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| External Descriptors | |
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| Physico-Chemical Properties - Experimental |
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| Property | Value | Reference |
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| Experimental logP | Not Available | |
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| Experimental Water Solubility | Not Available | |
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| Melting Point | Not Available | |
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| Foods of Origin |
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| Food | Content Range | Average | Reference |
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| Food | | | Reference |
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| Production Data |
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| Production Method | commercial |
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| Production Method Reference | Not Available |
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| Production Method Reference File | Not Available |
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| Quantity Available | Production upon request, up to 100 mg |
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| Delivery Time | Not Available |
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| Storage Form | solid |
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| Storage Conditions | -80°C |
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| Stability | Not Available |
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| Purity | Not Available |
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| Spectra |
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| Spectral Data Upon Request | Not Available |
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| Provider Information |
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| Commercial Vendors |
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| AKSci | 1632AB |
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| Toronto Research Chemicals | T899980 |
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