Record Information
Version1.0
Creation date2015-10-09 22:32:41 UTC
Update date2017-01-19 02:36:36 UTC
FoodComEx IDPC000793
FoodDB RecordFDB014518
Chemical Information
Name1-Methylguanine
DescriptionPresent in Chinese cabbage (Brassica chinensis), and other plants 1-Methylguanine is a naturally occurring modified purine derived from tRNA, found in elevated levels in the serum and urine of cancer patients. (PMID: 2413515); Increase of 1-methylguanine in the urine of colorectal tumor bearing patients, has been justified either by a more rapid turnover of nucleic acids in tumor tissue or by an increase in the extent of their methylation. (PMID: 9069642)
CAS Number938-85-2
Structure
Thumb
Synonyms
SynonymSource
1-methyl-(8CI)-guaninebiospider
1-methyl-guaninebiospider
2-amino-1-methyl-1,9-dihydro-6H-purin-6-onebiospider
2-Amino-1,7-dihydro-1-methyl-6H-purin-6-onebiospider
2-Amino-1,7-dihydro-1-methyl-6H-purin-6-one, 9CIdb_source
2-Amino-6-hydroxy-1-methylpurinebiospider
6H-Purin-6-one, 2-amino-1,7-dihydro-1-methyl-biospider
6H-Purin-6-one, 2-amino-1,7-dihydro-1-methyl- (9CI)biospider
Guanine, 1-methyl-biospider
Guanine, 1-methyl- (8CI)biospider
N1-Methylguaninebiospider
rRNA containing N1-methylguaninebiospider
Chemical FormulaC12H14N10O2
IUPAC namebis(2-imino-1-methyl-2,3,6,9-tetrahydro-1H-purin-6-one)
InChI IdentifierInChI=1S/2C6H7N5O/c2*1-11-5(12)3-4(9-2-8-3)10-6(11)7/h2*2H,1H3,(H2,7,10)(H,8,9)
InChI KeyXIUGXLYVSVNLRR-UHFFFAOYSA-N
Isomeric SMILESCN1C(N)=NC2=C(NC=N2)C1=O.CN1C(N)=NC2=C(N=CN2)C1=O
Average Molecular Weight330.3054
Monoisotopic Molecular Weight330.130119742
Chemical Taxonomy
ClassificationNot classified
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logPNot Available
Experimental Water SolubilityNot Available
Melting PointMp 350°DFC
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 10 mg
Delivery TimeNot Available
Storage Formsolid
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
Not Available