Record Information
Version1.0
Creation date2015-10-09 22:32:12 UTC
Update date2017-01-19 02:36:34 UTC
FoodComEx IDPC000718
FoodDB RecordFDB023115
Chemical Information
NameN-Methylnicotinamide
DescriptionN-methylnicotinamide is a metabolite of niacin (or nicotinamide) and is commonly found in human urine. However low levels of urinary excretion of N-methylnicotinamide indicates niacin deficiency. (PMID: 16207585). In patients with liver cirrhosis nicotinamide methylation is increased leading to a rise in urinary N-methylnicotinamide. The hyperfunction of this methylating pathway might play a protective role against the toxic effect of intracellular accumulation of nicotinamide deriving from the catabolic state of cirrhosis. N-methylnicotinamide is known to inhibit choline transport and reduce choline clearance out of the brain. [HMDB]
CAS Number114-33-0
Structure
Thumb
Synonyms
SynonymSource
3-(Methylcarbamoyl)pyridinehmdb
3-(N-Methylcarbamoyl)pyridinehmdb
N -Methyl nicotineamidehmdb
N-Methyl nicotineamideChEBI
N-Methyl-3-pyridinecarboxamidehmdb
N-methylnicotinamidehmdb
N-Methylpyridine-3-carboxamideChEBI
Nicotinate methylamideGenerator
Nicotinic acid methylamidehmdb
Chemical FormulaC7H8N2O
IUPAC nameN-methylpyridine-3-carboxamide
InChI IdentifierInChI=1S/C7H8N2O/c1-8-7(10)6-3-2-4-9-5-6/h2-5H,1H3,(H,8,10)
InChI KeyZYVXHFWBYUDDBM-UHFFFAOYSA-N
Isomeric SMILESCNC(=O)C1=CN=CC=C1
Average Molecular Weight136.1512
Monoisotopic Molecular Weight136.063662888
Chemical Taxonomy
ClassificationNot classified
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logPNot Available
Experimental Water SolubilityNot Available
Melting PointNot Available
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 100 mg
Delivery TimeNot Available
Storage Formsolid
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
AKSci V1451
Cayman Chemical 21850
Cayman Chemical HMDB0003152
MetaSci HMDB0003152
Toronto Research Chemicals M321170