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Cysteamine (PC000686)

Record Information
Version1.0
Creation date2015-10-09 22:31:57 UTC
Update date2017-01-19 02:36:32 UTC
FoodComEx IDPC000686
FoodDB RecordFDB023091
Chemical Information
NameCysteamine
DescriptionCysteamine is a product of the constitutive degradation of coenzyme A, a process that occurs in all tissues, although some tissues such as brain and heart may have exceptionally high coenzyme A turnover rates. Cysteamine has only one known function, and that is as a precursor for the formation of hypotaurine, which is subsequently oxidized to taurine. The rate of cysteamine production as a result of coenzyme A breakdown is not well understood but it is clear that cysteamine levels are not as dramatically affected by dietary habits as are cysteine levels. Cysteamine is generated from hypotaurine by cysteamine dioxygenase (EC:1.13.11.19), an enzyme that was recently identified in mammals (PMID: 17581819). Cysteamine is the simplest stable aminothiol found in the body. It is used in the treatment of disorders of cystine excretion. Cysteamine cleaves the disulfide bond with cysteine to produce molecules that can escape the metabolic defect in cystinosis and cystinuria. Cyst(e)amine may also serve as an endogenous regulator of immune system activity as well as a potential therapeutic agent for the treatment of Huntington disease. Cysteamine is also used as a radiation-protective agent that oxidizes in air to form cystamine. It can be given intravenously or orally to treat radiation sickness. -- Wikipedia [HMDB]
CAS Number60-23-1
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
SynonymSource
(2-Mercaptoethyl)aminehmdb
2-Amino-1-ethanethiolhmdb
2-amino-ETHANETHIOLChEBI
2-Aminoethanethiolhmdb
2-Aminoethyl mercaptanhmdb
2-Mercaptoethanaminehmdb
Aminoethyl mercaptanhmdb
b-Aminoethanethiolhmdb
b-Aminoethylthiolhmdb
b-MEAGenerator
b-Mercaptoethylaminehmdb
Becaptanhmdb
beta-Aminoethanethiolhmdb
beta-Aminoethylthiolhmdb
beta-MEAChEBI
beta-Mercaptoethylaminehmdb
CASHhmdb
Cisteaminahmdb
Cysteamidehmdb
Cysteaminhmdb
Cysteaminehmdb
CysteaminiumHMDB
Cysteinaminehmdb
Decarboxycysteinehmdb
Ethanethiolaminehmdb
Lambratenhmdb
Lambratenehmdb
Mecraminehmdb
Mercaminhmdb
Mercaminehmdb
Mercaptaminhmdb
MercaptaminaChEBI
MercaptamineChEBI
MercaptaminumChEBI
Merkaminhmdb
Riaconhmdb
Thioethanolaminehmdb
β-aminoethanethiolGenerator
β-aminoethylthiolGenerator
β-meaGenerator
β-mercaptoethylamineGenerator
Chemical FormulaC2H7NS
IUPAC name2-aminoethane-1-thiol
InChI IdentifierInChI=1S/C2H7NS/c3-1-2-4/h4H,1-3H2
InChI KeyUFULAYFCSOUIOV-UHFFFAOYSA-N
Isomeric SMILESNCCS
Average Molecular Weight77.149
Monoisotopic Molecular Weight77.029919919
Chemical Taxonomy
Description Belongs to the class of organic compounds known as alkylthiols. These are organic compounds containing the thiol functional group linked to an alkyl chain.
KingdomOrganic compounds
Super ClassOrganosulfur compounds
ClassThiols
Sub ClassAlkylthiols
Direct ParentAlkylthiols
Alternative Parents
Substituents
  • Alkylthiol
  • Organic nitrogen compound
  • Organopnictogen compound
  • Hydrocarbon derivative
  • Primary amine
  • Organonitrogen compound
  • Primary aliphatic amine
  • Amine
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logPNot Available
Experimental Water SolubilityNot Available
Melting PointNot Available
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 1 g
Delivery TimeNot Available
Storage Formsolid
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
Not Available