| Record Information |
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| Version | 1.0 |
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| Creation date | 2015-10-09 22:31:55 UTC |
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| Update date | 2017-01-19 02:36:32 UTC |
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| FoodComEx ID | PC000679 |
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| FoodDB Record | FDB023426 |
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| Chemical Information |
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| Name | FAPy-adenine |
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| Description | Fapy-adenine is an oxidized DNA base. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases. (PMID 15116424)
Oxidative stress damage to DNA bases may contribute to neuronal loss in Alzheimer's disease (AD). Increased levels were observed in parietal, temporal, occipital, and frontal lobe, superior temporal gyrus, and hippocampus areas of the brain in patients with AD. (PMID 9109533) [HMDB] |
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| CAS Number | 5122-36-1 |
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| Structure | |
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| Synonyms | | Synonym | Source |
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| 4,6-Diamino-5-(formylamino)pyrimidine | hmdb | | 4,6-Diamino-5-formamidopyrimidine | hmdb | | 4,6-Diamino-5-N-formamidopyrimidine | hmdb | | 4,6-Diamino-5-pyrimidinylformamide | hmdb | | FAPY | hmdb | | Fapyade | hmdb | | N-(4,6-diamino-5-pyrimidinyl)-Formamide | hmdb | | N-(4,6-Diamino-5-pyrimidinyl)formamide | hmdb |
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| Chemical Formula | C5H7N5O |
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| IUPAC name | N-(4,6-diaminopyrimidin-5-yl)formamide |
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| InChI Identifier | InChI=1S/C5H7N5O/c6-4-3(10-2-11)5(7)9-1-8-4/h1-2H,(H,10,11)(H4,6,7,8,9) |
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| InChI Key | MVYUVUOSXNYQLL-UHFFFAOYSA-N |
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| Isomeric SMILES | NC1=NC=NC(N)=C1NC=O |
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| Average Molecular Weight | 153.142 |
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| Monoisotopic Molecular Weight | 153.065059871 |
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| Chemical Taxonomy |
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| Description | Belongs to the class of organic compounds known as aminopyrimidines and derivatives. These are organic compounds containing an amino group attached to a pyrimidine ring. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions. |
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| Kingdom | Organic compounds |
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| Super Class | Organoheterocyclic compounds |
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| Class | Diazines |
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| Sub Class | Pyrimidines and pyrimidine derivatives |
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| Direct Parent | Aminopyrimidines and derivatives |
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| Alternative Parents | |
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| Substituents | - Aminopyrimidine
- Hydropyrimidine
- Imidolactam
- Heteroaromatic compound
- Carboximidic acid
- Carboximidic acid derivative
- Propargyl-type 1,3-dipolar organic compound
- Organic 1,3-dipolar compound
- Azacycle
- Primary amine
- Organooxygen compound
- Organonitrogen compound
- Organic oxygen compound
- Amine
- Organopnictogen compound
- Organic nitrogen compound
- Hydrocarbon derivative
- Aromatic heteromonocyclic compound
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| Molecular Framework | Aromatic heteromonocyclic compounds |
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| External Descriptors | |
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| Physico-Chemical Properties - Experimental |
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| Property | Value | Reference |
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| Experimental logP | Not Available | |
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| Experimental Water Solubility | Not Available | |
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| Melting Point | Not Available | |
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| Foods of Origin |
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| Food | Content Range | Average | Reference |
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| Food | | | Reference |
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| Production Data |
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| Production Method | commercial |
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| Production Method Reference | Not Available |
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| Production Method Reference File | Not Available |
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| Quantity Available | Production upon request, up to 20 mg |
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| Delivery Time | Not Available |
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| Storage Form | solid |
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| Storage Conditions | -80°C |
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| Stability | Not Available |
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| Purity | Not Available |
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| Spectra |
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| Spectral Data Upon Request | Not Available |
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| Provider Information |
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| Commercial Vendors |
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| Not Available |
