FComEx: Clotrimazole (PC000555)

Record Information

Version

1.0

Creation date

2015-10-09 22:31:18 UTC

Update date

2017-01-19 02:36:27 UTC

FoodComEx ID

PC000555

FoodDB Record

FDB022740

Chemical Information

Name

Clotrimazole

Description

Clotrimazole is an imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. -- Pubchem; There is the potential for drug interactions with Clotrimazole if taken orally, as it is a potent, specific inhibitor of cytochrome P450 oxidase enzymes and so may alter the metabolism of other drugs.; Clotrimazole is an antifungal medication commonly used in the treatment of fungal infections of both humans and animals such as vaginal yeast infections and ringworm. -- Wikipedia; An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.; Clotrimazole is a potent, specific inhibitor of cytochrome P450 oxidase enzymes. Hence, it may alter the metabolism of other drugs particularly if taken orally. -- Wikipedia; Clotrimazole is an antifungal medication commonly used in the treatment of fungal infections of both humans and animals such as vaginal yeast infections and ringworm. It also used to treat athlete's foot and jock itch. [HMDB]

CAS Number

23593-75-1

Structure

MOL SDF 3D-SDF PDB SMILES InChI View 3D Structure

Synonyms

Synonym	Source
(Chlorotrityl)imidazole	hmdb
1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole	ChEBI
1-(a-(2-Chlorophenyl)benzhydryl)imidazole	Generator
1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole	ChEBI
1-(O-chloro-a,a-Diphenylbenzyl)imidazole	Generator
1-(O-chloro-alpha,alpha-Diphenylbenzyl)imidazole	ChEBI
1-(O-chloro-α,α-diphenylbenzyl)imidazole	Generator
1-(o-Chlorotrityl)imidazole	hmdb
1-(α-(2-chlorophenyl)benzhydryl)imidazole	Generator
Canesten	hmdb
Canesten 1-Day Cream Combi-Pak	hmdb
Canesten 1-Day Therapy	hmdb
Canesten 3-Day Therapy	hmdb
Canesten 6-Day Therapy	hmdb
Canesten Combi-Pak 1-Day Therapy	hmdb
Canesten Combi-Pak 3-Day Therapy	hmdb
Canesten Cream	hmdb
Canesten Solution	hmdb
Canestine	hmdb
Chlotrimazole	hmdb
Clotrimaderm	hmdb
Clotrimaderm Cream	hmdb
Clotrimazol	hmdb
Clotrimazole	hmdb
Clotrimazolum	hmdb
Desamix F	hmdb
Empecid	hmdb
Fem Care	hmdb
FemCare	hmdb
Gyne lotrimin	hmdb
Gyne-lotrimin	hmdb
Gyne-Lotrimin 3	hmdb
Gyne-Lotrimin 3 Combination Pack	hmdb
Gyne-Lotrimin Combination Pack	hmdb
Gyne-Lotrimin3	hmdb
Gyne-Lotrimin3 Combination Pack	hmdb
Gynix	hmdb
Lopac-C-6019	hmdb
Lotrimax	hmdb
Lotrimin	hmdb
Lotrimin AF	hmdb
Lotrimin AF Cream	hmdb
Lotrimin AF Jock-Itch Cream	hmdb
Lotrimin AF Lotion	hmdb
Lotrimin AF Solution	hmdb
Lotrimin Cream	hmdb
Lotrimin Lotion	hmdb
Lotrimin Solution	hmdb
Lotrisone	hmdb
Mono-baycuten	hmdb
Monobaycuten	hmdb
Mycelax	hmdb
Mycelex	hmdb
Mycelex 7	hmdb
Mycelex Cream	hmdb
Mycelex G	hmdb
Mycelex OTC	hmdb
Mycelex Solution	hmdb
Mycelex Troches	hmdb
Mycelex Twin Pack	hmdb
Mycelex-7	hmdb
Mycelex-7 Combination Pack	hmdb
Mycelex-G	hmdb
Mycelex: MycosporinRimazole	hmdb
Myclo Cream	hmdb
Myclo Solution	hmdb
Myclo Spray Solution	hmdb
Myclo-Gyne	hmdb
Mycosporin	hmdb
Mykosporin	hmdb
Neo-Zol Cream	hmdb
Otomax	hmdb
Pedisafe	hmdb
Prestwick_120	hmdb
Rimazole	hmdb
Tibatin	hmdb
Trimysten	hmdb
Trivagizole 3	hmdb
Veltrim	hmdb