FComEx: N-(2-Hydroxybenzoyl)glycine (PC000383)

Record Information

Version

1.0

Creation date

2015-10-09 22:30:22 UTC

Update date

2017-01-19 02:36:21 UTC

FoodComEx ID

PC000383

FoodDB Record

FDB010505

Chemical Information

Name

N-(2-Hydroxybenzoyl)glycine

Description

Constituent of milk Salicyluric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:; acyl-CoA + glycine < -- > CoA + N-acylglycine; The induction of the salicyluric acid formation is one of the saturable pathways of salicylate elimination.; The formation of the methyl ester of salicyluric acid is observed during the quantitation of salicyluric acid and other salicylate metabolites in urine by high-pressure liquid chromatography. This methyl ester formation causes artificially low values for salicyluric acid and high values for salicylic acid.; (PMID: 6101164, 6857178). N-(2-Hydroxybenzoyl)glycine is found in milk and milk products.

CAS Number

487-54-7

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
((2-hydroxybenzoyl)amino)acetic acid	biospider
(2-hydroxybenzamido)acetic acid	biospider
(2-Hydroxybenzoyl)glycine	biospider
[(2-Hydroxybenzoyl)amino]acetate	biospider
[(2-Hydroxybenzoyl)amino]acetic acid	biospider
2-Hydroxybenzamidoacetic acid	db_source
2-hydroxybenzoylaminoacetate	biospider
2-hydroxybenzoylaminoacetic acid	biospider
2-Hydroxybenzoylglycine	biospider
2-Hydroxyhippurate	biospider
2-Hydroxyhippuric acid	biospider
Glycine, N-(2-hydroxybenzoyl)-	biospider
Glycine, N-(2-hydroxybenzoyl)- (9CI)	biospider
Glycine, n-salicyloyl-	biospider
Hippuric acid, o-hydroxy-	biospider
N-(2-Hydroxybenzoyl)-glycine	biospider
N-o-hydroxybenzoylglycine	biospider
N-salicyloylglycine	biospider
O-hydroxy-hippurate	biospider
O-hydroxy-hippuric acid	biospider
O-Hydroxyhippate	Generator
O-Hydroxyhippic acid	Generator
O-hydroxyhippurate	biospider
O-hydroxyhippuric acid	biospider
o-Hydroxyhippuric acid, 8CI	db_source
Ortho-hydroxyhippurate	biospider
Ortho-hydroxyhippuric acid	biospider
Salicylglycine	biospider
Salicyloylaminoacetic acid	db_source
Salicyloylglycine	db_source
Salicylurate	biospider
Salicyluric acid	db_source

Chemical Formula

C9H9NO4

IUPAC name

2-[(2-hydroxyphenyl)formamido]acetic acid

InChI Identifier

InChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13)

InChI Key

ONJSZLXSECQROL-UHFFFAOYSA-N

Isomeric SMILES

OC(=O)CNC(=O)C1=CC=CC=C1O

Average Molecular Weight

195.1721

Monoisotopic Molecular Weight

195.053157781

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as hippuric acids. Hippuric acids are compounds containing hippuric acid, which consists of a of a benzoyl group linked to the N-terminal of a glycine.

Kingdom

Organic compounds

Super Class

Benzenoids

Class

Benzene and substituted derivatives

Sub Class

Benzoic acids and derivatives

Direct Parent

Hippuric acids

Alternative Parents