Record Information
Version1.0
Creation date2015-10-09 22:30:18 UTC
Update date2017-01-19 02:36:21 UTC
FoodComEx IDPC000374
FoodDB RecordFDB021883
Chemical Information
NameAldosterone
DescriptionAldosterone is a steroid hormone produced by the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. Specifically it regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It is the sole endogenous member of the class of mineralocorticoids. Aldosterone increases the permeability of the apical (luminal) membrane of the kidney's collecting ducts to potassium and sodium and activates their basolateral Na+/K+ pumps, stimulating ATP hydrolysis, reabsorbing sodium (Na+) ions and water into the blood, and excreting potassium (K+) ions into the urine. [HMDB]
CAS Number52-39-1
Structure
Thumb
Synonyms
SynonymSource
(+)-Aldosteronehmdb
(11b)-11,21-dihydroxy-3,20-dioxo-pregn-4-en-18-alhmdb
(11beta)-11,21-dihydroxy-3,20-dioxo-Pregn-4-en-18-alhmdb
11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-13-carbaldehydehmdb
11,21-Dihydroxy-3,20-dioxopregn-4-en-18-alhmdb
11b,21-dihydroxy-3,20-dioxo-pregn-4-en-18-alhmdb
11beta,21-Dihydroxy-3,20-diketo-4-pregnen-18-alhmdb
11beta,21-Dihydroxy-3,20-diketopregn-4-ene-18-alhmdb
11beta,21-Dihydroxy-3,20-dioxo-pregn-4-en-18-alhmdb
11beta,21-Dihydroxypregn-4-ene-3,18,20-trionehmdb
18-Formyl-11beta,21-dihydroxy-4-pregnene-3,20-dionehmdb
18-Oxocorticosteronehmdb
Aldocortenhmdb
Aldocortenehmdb
Aldocortinhmdb
aldosteronehmdb
Aldosteronumhmdb
d-Aldosteronehmdb
delta-Aldosteronehmdb
Electrocortinhmdb
Elektrocortinhmdb
Reichstein Xhmdb
Chemical FormulaNot Available
IUPAC nameNot Available
InChI IdentifierInChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14?,15?,16-,17+,19?,20+,21-/m1/s1
InChI KeyPQSUYGKTWSAVDQ-SRPWZAMTSA-N
Isomeric SMILESC[C@]12CCC(=O)C=C1CCC1C3CC[C@H](C(=O)CO)[C@]3(C[C@H](O)C21)C=O
Average Molecular Weight360.444
Monoisotopic Molecular Weight360.193674006
Chemical Taxonomy
Description Belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassSteroids and steroid derivatives
Sub ClassHydroxysteroids
Direct Parent21-hydroxysteroids
Alternative Parents
Substituents
  • Progestogin-skeleton
  • 21-hydroxysteroid
  • 20-oxosteroid
  • Pregnane-skeleton
  • 18-oxosteroid
  • 3-oxo-delta-4-steroid
  • 3-oxosteroid
  • Oxosteroid
  • 11-beta-hydroxysteroid
  • 11-hydroxysteroid
  • Delta-4-steroid
  • Cyclohexenone
  • Cyclic alcohol
  • Alpha-hydroxy ketone
  • Ketone
  • Secondary alcohol
  • Cyclic ketone
  • Alcohol
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organic oxide
  • Organic oxygen compound
  • Carbonyl group
  • Primary alcohol
  • Aldehyde
  • Aliphatic homopolycyclic compound
Molecular FrameworkAliphatic homopolycyclic compounds
External DescriptorsNot Available
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logPNot Available
Experimental Water SolubilityNot Available
Melting PointNot Available
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 20 mg
Delivery TimeNot Available
Storage Formsolid
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
AKSci 1604AH
Cayman Chemical 15273
Toronto Research Chemicals A514700
Toronto Research Chemicals KIT0300