FComEx: L-Kynurenine (PC000371)

Record Information

Version

1.0

Creation date

2015-10-09 22:30:16 UTC

Update date

2017-01-19 02:36:21 UTC

FoodComEx ID

PC000371

FoodDB Record

FDB022181

Chemical Information

Name

L-Kynurenine

Description

Kynurenine is a metabolite of the amino acid tryptophan used in the production of niacin. L-kynurenine is a central compound of the pathway of tryptophan metabolism pathway since it can change to the neuroprotective agent kynurenic acid or to the neurotoxic agent quinolinic acid. The break-up of these endogenous compounds' balance can be observable in many disorders. It can occur in neurodegenerative disorders, such as Parkinson's disease, Huntington's and Alzheimer's disease, in stroke, in epilepsy, in multiple sclerosis, in amyotrophic lateral sclerosis, and in mental failures, such as schizophrenia and depression. [HMDB]

CAS Number

2922-83-0

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
(2S)-2-amino-4-(2-Aminophenyl)-4-oxobutanoate	Generator
(2S)-2-amino-4-(2-Aminophenyl)-4-oxobutanoic acid	ChEBI
(alphaS)-alpha,2-diamino-3-hydroxy-gamma-oxo-Benzenebutanoate	hmdb
(alphaS)-alpha,2-diamino-3-hydroxy-gamma-oxo-Benzenebutanoic acid	hmdb
(S)-alpha,2-diamino-3-hydroxy-gamma-oxo-Benzenebutanoate	hmdb
(S)-alpha,2-diamino-3-hydroxy-gamma-oxo-Benzenebutanoic acid	hmdb
3-(3-Hydroxyanthraniloyl)-L-alanine	HMDB
3-anthraniloyl-Alanine	hmdb
3-anthraniloyl-L-alanine	hmdb
3-Anthraniloylalanine	hmdb
3-Hydroxy-L-kynurenine	HMDB
alpha,2-diamino-gamma-oxo-Benzenebutanoate	hmdb
alpha,2-diamino-gamma-oxo-Benzenebutanoic acid	hmdb
dl-Kynurenine	hmdb
DL-Kynureninefree base	hmdb
Kynurenin	hmdb
KYNURENINE	ChEBI
Quinurenine	hmdb

Chemical Formula

C10H12N2O3

IUPAC name

(2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid

InChI Identifier

InChI=1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m0/s1

InChI Key

YGPSJZOEDVAXAB-QMMMGPOBSA-N

Isomeric SMILES

N[C@@H](CC(=O)C1=CC=CC=C1N)C(O)=O

Average Molecular Weight

208.2139

Monoisotopic Molecular Weight

208.08479226

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbonyl compounds

Direct Parent

Alkyl-phenylketones

Alternative Parents