FComEx: Quinolinic acid (PC000364)

Record Information

Version

1.0

Creation date

2015-10-09 22:30:11 UTC

Update date

2017-01-19 02:36:21 UTC

FoodComEx ID

PC000364

FoodDB Record

FDB021913

Chemical Information

Name

Quinolinic acid

Description

A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. Quinolinic acid (QUIN) is a product of tryptophan metabolism that can act as an endogenous brain excitotoxin when released by activated macrophages. (Valle et. al, Brain 127:1047 (2004)) [HMDB]. Quinolinic acid is found in many foods, some of which are biscuit, enokitake, winged bean, and black huckleberry.

CAS Number

89-00-9

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
2,3-pyridinedicarboxylate	hmdb
2,3-pyridinedicarboxylic acid	hmdb
3,4-Pyridinedicarboxylic acid	hmdb
Pyridin-2,3-dicarbonsaeure	hmdb
pyridine-2,3-carboxylate	hmdb
Pyridine-2,3-dicarboxylate	hmdb
Pyridine-2,3-dicarboxylic acid	hmdb
Pyridine-3,4-dicarboxylic acid	hmdb
Quinolinate	hmdb
Quinolinic acid	hmdb

Chemical Formula

C7H5NO4

IUPAC name

pyridine-2,3-dicarboxylic acid

InChI Identifier

InChI=1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)

InChI Key

GJAWHXHKYYXBSV-UHFFFAOYSA-N

Isomeric SMILES

OC(=O)C1=CC=CN=C1C(O)=O

Average Molecular Weight

167.1189

Monoisotopic Molecular Weight

167.021857653

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pyridinecarboxylic acids. Pyridinecarboxylic acids are compounds containing a pyridine ring bearing a carboxylic acid group.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Pyridines and derivatives

Sub Class

Pyridinecarboxylic acids and derivatives

Direct Parent

Pyridinecarboxylic acids

Alternative Parents