Record Information
Version1.0
Creation date2015-10-09 22:29:38 UTC
Update date2017-01-19 02:36:19 UTC
FoodComEx IDPC000284
FoodDB RecordFDB008298
Chemical Information
NameAcetamide
DescriptionAcetamide, also known as ethanamid or acetic acid amide, belongs to the class of organic compounds known as carboximidic acids. These are organic acids with the general formula RC(=N)-OH. Acetamide is soluble in water and low molecular mass alcohols. It forms deliquescent hexagonal crystals that are odorless when pure (DOI: 10.1002/14356007.a01_045.pub3), but it frequently has a mousy odor. Pure acetamide has a bitter taste. Acetamide is used as a solvent and as a plasticizer (DOI:10.1002/14356007.a01_045.pub3). Acetamide has been classified by the International Agency for Research on Cancer (IARC) as a Group 2B possible human carcinogen (PMID: 10507919). However, further studies need to be conducted to better understand the potential in vivo genotoxicity of acetamide (PMID: 31470077). It has also been investigated as a residue from some pesticides and as an impurity in the manufacture of pharmaceuticals (DOI: 10.1021/op200205b). Acetamide has been identified in milk, eggs, and meat (PMID: 29186951).
CAS Number60-35-5
Structure
Thumb
Synonyms
SynonymSource
AcetamidChEBI
Acetate amideGenerator
Acetic acid amidebiospider
Acetimidic acidHMDB
Acetimidic acid (van)biospider
ACMbiospider
Amid kyseliny octovebiospider
AzetamidChEBI
CH3CONH2biospider
EssigsaeureamidChEBI
EthanamidChEBI
Ethanamidedb_source
Methanecarboxamidedb_source
Chemical FormulaC2H5NO
IUPAC nameacetamide
InChI IdentifierInChI=1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4)
InChI KeyDLFVBJFMPXGRIB-UHFFFAOYSA-N
Isomeric SMILESCC(N)=O
Average Molecular Weight59.0672
Monoisotopic Molecular Weight59.037113787
Chemical Taxonomy
Description belongs to the class of organic compounds known as carboximidic acids. These are organic acids with the general formula RC(=N)-OH (R=H, organic group).
KingdomOrganic compounds
Super ClassOrganic acids and derivatives
ClassCarboximidic acids and derivatives
Sub ClassCarboximidic acids
Direct ParentCarboximidic acids
Alternative Parents
Substituents
  • Carboximidic acid
  • Organic nitrogen compound
  • Organic oxygen compound
  • Organopnictogen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organonitrogen compound
  • Aliphatic acyclic compound
Molecular FrameworkAliphatic acyclic compounds
External Descriptors
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logP-1.26HANSCH,C ET AL. (1995)
Experimental Water Solubility2250 mg/mL at 25 oCYALKOWSKY,SH & DANNENFELSER,RM (1992)
Melting PointMp 82-83°DFC
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 1 g
Delivery TimeNot Available
Storage FormNot Available
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
AKSci C878
AKSci J93173
Glentham GL9642
Glentham GL1221
MetaSci HMDB0031645
Sigma-Aldrich HMDB0031645
Toronto Research Chemicals A133060