| Record Information |
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| Version | 1.0 |
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| Creation date | 2015-10-09 22:29:36 UTC |
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| Update date | 2017-01-19 02:36:18 UTC |
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| FoodComEx ID | PC000272 |
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| FoodDB Record | FDB005421 |
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| Chemical Information |
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| Name | Methylguanidine |
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| Description | Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibits anti-inflammatory effects. Methylguanidine is synthesized from creatinine concomitant with the synthesis of hydrogen peroxide from endogenous substrates in peroxisomes. Recent evidence suggests that methylguanidine significantly inhibits iNOS activity and TNF- release. This means that methylguandine can attenuate the degree of inflammation and tissue damage associated with endotoxic shock. Methylguanidine is found in loquat and apple. |
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| CAS Number | 471-29-4 |
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| Structure | |
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| Synonyms | | Synonym | Source |
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| 1-methylguanidine | biospider | | Guanidine, methyl- | biospider | | Methylguanidin | biospider | | Methylguanidine | biospider | | MGX | biospider | | Monomethyl guanidin | biospider | | Monomethylguanidine | biospider | | N-methylguanidine | biospider | | N1-Methylguanidine | biospider |
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| Chemical Formula | C2H7N3 |
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| IUPAC name | N-methylguanidine |
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| InChI Identifier | InChI=1S/C2H7N3/c1-5-2(3)4/h1H3,(H4,3,4,5) |
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| InChI Key | CHJJGSNFBQVOTG-UHFFFAOYSA-N |
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| Isomeric SMILES | CNC(N)=N |
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| Average Molecular Weight | 73.0971 |
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| Monoisotopic Molecular Weight | 73.063997239 |
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| Chemical Taxonomy |
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| Description | Belongs to the class of organic compounds known as guanidines. Guanidines are compounds containing a guanidine moiety, with the general structure (R1R2N)(R3R4N)C=N-R5. |
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| Kingdom | Organic compounds |
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| Super Class | Organic nitrogen compounds |
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| Class | Organonitrogen compounds |
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| Sub Class | Guanidines |
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| Direct Parent | Guanidines |
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| Alternative Parents | |
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| Substituents | - Guanidine
- Carboximidamide
- Organopnictogen compound
- Hydrocarbon derivative
- Imine
- Aliphatic acyclic compound
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| Molecular Framework | Aliphatic acyclic compounds |
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| External Descriptors | |
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| Physico-Chemical Properties - Experimental |
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| Property | Value | Reference |
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| Experimental logP | Not Available | |
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| Experimental Water Solubility | 1.78 mg/mL at 20 oC | GREENWALD,I (1926) |
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| Melting Point | Not Available | |
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| Foods of Origin |
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| Food | Content Range | Average | Reference |
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| Food | | | Reference |
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| Production Data |
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| Production Method | commercial |
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| Production Method Reference | Not Available |
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| Production Method Reference File | Not Available |
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| Quantity Available | Production upon request, up to 1 g |
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| Delivery Time | Not Available |
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| Storage Form | solid |
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| Storage Conditions | -80°C |
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| Stability | Not Available |
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| Purity | Not Available |
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| Spectra |
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| Spectral Data Upon Request | Not Available |
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| Provider Information |
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| Commercial Vendors |
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| Not Available |
