Record Information
Version1.0
Creation date2015-10-09 22:29:28 UTC
Update date2017-01-19 02:36:18 UTC
FoodComEx IDPC000254
FoodDB RecordFDB022550
Chemical Information
Name6-Phosphogluconic acid
Description6-Phosphogluconic acid, also known as 6-phospho-D-gluconate or gluconate 6-phosphate, belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit. A gluconic acid phosphate having the phosphate group at the 6-position. 6-Phosphogluconic acid is an extremely weak basic (essentially neutral) compound (based on its pKa). 6-Phosphogluconic acid exists in all living species, ranging from bacteria to humans. Within humans, 6-phosphogluconic acid participates in a number of enzymatic reactions. In particular, 6-phosphogluconic acid can be biosynthesized from gluconolactone through its interaction with the enzyme 6-phosphogluconolactonase. In addition, 6-phosphogluconic acid can be converted into D-ribulose 5-phosphate through the action of the enzyme 6-phosphogluconate dehydrogenase, decarboxylating. In humans, 6-phosphogluconic acid is involved in the metabolic disorder called the glucose-6-phosphate dehydrogenase deficiency pathway. Outside of the human body, 6-Phosphogluconic acid has been detected, but not quantified in, several different foods, such as teffs, chinese chestnuts, cottonseeds, irish moss, and red beetroots. This could make 6-phosphogluconic acid a potential biomarker for the consumption of these foods.
CAS Number921-62-0
Structure
Thumb
Synonyms
SynonymSource
6-O-D-GluconateChEBI
6-O-D-Gluconic acidGenerator
6-O-ONO-D-Gluconic acidHMDB
6-O-phosphono-D-gluconic acidhmdb
6-OgluconateHMDB
6-Ogluconic acidHMDB
6-p-gluconatehmdb
6-Phospho-D-gluconatehmdb
6-Phospho-D-gluconic acidhmdb
6-phosphogluconatehmdb
6-phosphogluconic acidhmdb
D-Gluconic acid 6-(dihydrogen ate)HMDB
D-Gluconic acid 6-(dihydrogen phosphate)hmdb
D-Gluconic acid 6-ateHMDB
D-Gluconic acid 6-phosphatehmdb
Gluconic acid-6-ateHMDB
gluconic acid-6-phosphatehmdb
Chemical FormulaNot Available
IUPAC nameNot Available
InChI IdentifierInChI=1S/C6H13O10P/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15)/t2-,3-,4+,5-/m1/s1
InChI KeyBIRSGZKFKXLSJQ-SQOUGZDYSA-N
Isomeric SMILESO[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O
Average Molecular Weight276.1352
Monoisotopic Molecular Weight276.024633148
Chemical Taxonomy
ClassificationNot classified
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logPNot Available
Experimental Water SolubilityNot Available
Melting PointNot Available
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 50 mg
Delivery TimeNot Available
Storage Formsolid
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
AKSci 5568AC