FComEx: 2-Phenylaminoadenosine (PC000241)

Record Information

Version

1.0

Creation date

2015-10-09 22:29:24 UTC

Update date

2017-01-19 02:36:17 UTC

FoodComEx ID

PC000241

FoodDB Record

FDB022408

Chemical Information

Name

2-Phenylaminoadenosine

Description

Selective A2 adenosine receptor agonist; potent coronary vasodilator; weak inhibitor of adenosine uptake by rat cerebral cortical synaptosomes; used as a vasodilator agent; is a potent anti-inflammatory agent, acting at its four G protein coupled receptors. Topical treatment of adenosine to foot wounds in diabetes mellitus has been shown in lab animals to drastically increase tissue repair and reconstruction. Topical administration of adenosine for use in wound healing deficiencies and diabetes mellitus in humans is currently under clinical investigation. Adenosine is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a beta-N9-glycosidic bond. [HMDB]

CAS Number

53296-10-9

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
6-amino-2-phenylamino-9-b-D-ribofuranosyl-9H-purine	hmdb
6-amino-2-phenylamino-9-beta-delta-ribofuranosyl-9H-purine	hmdb

Chemical Formula

C16H18N6O4

IUPAC name

2-[6-amino-2-(phenylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI Identifier

InChI=1S/C16H18N6O4/c17-13-10-14(21-16(20-13)19-8-4-2-1-3-5-8)22(7-18-10)15-12(25)11(24)9(6-23)26-15/h1-5,7,9,11-12,15,23-25H,6H2,(H3,17,19,20,21)

InChI Key

SCNILGOVBBRMBK-UHFFFAOYSA-N

Isomeric SMILES

NC1=C2N=CN(C3OC(CO)C(O)C3O)C2=NC(NC2=CC=CC=C2)=N1

Average Molecular Weight

358.3519

Monoisotopic Molecular Weight

358.138953094

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as purine nucleosides. Purine nucleosides are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety.

Kingdom

Organic compounds

Super Class

Nucleosides, nucleotides, and analogues

Class

Purine nucleosides

Sub Class

Not Available

Direct Parent

Purine nucleosides

Alternative Parents