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Corticosterone (PC000206)

Record Information
Version1.0
Creation date2015-10-09 22:29:12 UTC
Update date2017-01-19 02:36:16 UTC
FoodComEx IDPC000206
FoodDB RecordFDB022684
Chemical Information
NameCorticosterone
DescriptionAn adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) [HMDB]
CAS Number50-22-6
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
SynonymSource
(11b)-11,21-Dihydroxypregn-4-ene-3,20-dioneGenerator
(11beta)-11,21-Dihydroxypregn-4-ene-3,20-dioneChEBI
(11β)-11,21-dihydroxypregn-4-ene-3,20-dioneGenerator
11-Hydroxycorticoaldosteronehmdb
11,21-Dihydroxypregn-4-ene-3,20-dionehmdb
11,21-Dihydroxyprogesteronehmdb
11b,21-Dihydroxy-4-pregnene-3,20-dioneGenerator
11b,21-DihydroxyprogesteroneGenerator
11beta,21-Dihydroxy-4-pregnene-3,20-dioneChEBI
11beta,21-DihydroxyprogesteroneChEBI
11β,21-dihydroxy-4-pregnene-3,20-dioneGenerator
11β,21-dihydroxyprogesteroneGenerator
17-Deoxycortisolhmdb
4-Pregnene-11 Corticosteronhmdb
Corticosteronehmdb
Kendall's compound Bhmdb
Reichstein's substance Hhmdb
Chemical FormulaC21H30O4
IUPAC name(1S,2R,10S,11S,14S,15S,17S)-17-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
InChI IdentifierInChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChI KeyOMFXVFTZEKFJBZ-HJTSIMOOSA-N
Isomeric SMILES[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@]([H])(O)C[C@]12C)C(=O)CO
Average Molecular Weight346.4605
Monoisotopic Molecular Weight346.214409448
Chemical Taxonomy
Description Belongs to the class of organic compounds known as 21-hydroxysteroids. These are steroids carrying a hydroxyl group at the 21-position of the steroid backbone.
KingdomOrganic compounds
Super ClassLipids and lipid-like molecules
ClassSteroids and steroid derivatives
Sub ClassHydroxysteroids
Direct Parent21-hydroxysteroids
Alternative Parents
Substituents
  • Progestogin-skeleton
  • 21-hydroxysteroid
  • Pregnane-skeleton
  • 20-oxosteroid
  • 3-oxo-delta-4-steroid
  • 3-oxosteroid
  • 11-hydroxysteroid
  • 11-beta-hydroxysteroid
  • Oxosteroid
  • Delta-4-steroid
  • Cyclohexenone
  • Alpha-hydroxy ketone
  • Cyclic alcohol
  • Ketone
  • Secondary alcohol
  • Cyclic ketone
  • Hydrocarbon derivative
  • Organic oxide
  • Carbonyl group
  • Organic oxygen compound
  • Alcohol
  • Organooxygen compound
  • Primary alcohol
  • Aliphatic homopolycyclic compound
Molecular FrameworkAliphatic homopolycyclic compounds
External Descriptors
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logPNot Available
Experimental Water SolubilityNot Available
Melting PointNot Available
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 400 mg
Delivery TimeNot Available
Storage Formsolid
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
AKSci 6866AB
Cayman Chemical 16063
MetaSci HMDB0001547
Sigma-Aldrich HMDB0001547
Toronto Research Chemicals C695700