FComEx: 2-Furancarboxylic acid (PC000098)

Record Information

Version

1.0

Creation date

2015-10-09 22:28:18 UTC

Update date

2017-01-19 02:36:12 UTC

FoodComEx ID

PC000098

FoodDB Record

FDB000951

Chemical Information

Name

2-Furancarboxylic acid

Description

Isolated from roots of Phaseolus vulgaris (kidney bean) Furoic acid is a metabolite that appears in the urine of workers occupationally exposed to furfural and is marker of exposure to this compound. Furfural is a heterocyclic aldehyde that is commonly used as a solvent in industry. It is readily absorbed into the body via the lungs and has significant skin absorption. Furfural is an irritant of the eyes, mucous membranes, and skin and is a central nervous system depressant. Furfural as a confirmed animal carcinogen with unknown relevance to humans (It has been suggested that is a substance that produces hepatic cirrhosis). Once in the body, furfural is metabolized rapidly via oxidation to the metabolite furoic acid, which is then conjugated with glycine and excreted in the urine in both free and conjugated forms. (PMID: 3751566, 4630229, 12587683). Furoic acid is a biomarker for the consumption of beer.

CAS Number

88-14-2

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
α-furancarboxylic acid	biospider
α-furoic acid	biospider
2-Carboxyfuran	biospider
2-furancarboxilic acid	biospider
2-Furancarboxylate	Generator
2-Furanoate	biospider
2-Furanoic acid	biospider
2-Furoate	biospider
2-Furoic acid	biospider
2-Furoic acid [per EINECS]	biospider
2-Furoic acid, 8CI	db_source
2-FUROIC ACID, PRACT	biospider
A-furancarboxylate	biospider
A-furancarboxylic acid	biospider
A-furoate	biospider
a-Furoic acid	db_source
Acide 2-furoique	ChEBI
Acido 2-furoico	ChEBI
Alpha-furancarboxylate	biospider
Alpha-furancarboxylic acid	biospider
Alpha-furoate	biospider
Alpha-furoic acid	biospider
B-furancarboxylate	biospider
B-furancarboxylic acid	biospider
B-furoate	biospider
B-furoic acid	biospider
Beta-furancarboxylate	biospider
Beta-furancarboxylic acid	biospider
Beta-furoate	biospider
Beta-furoic acid	biospider
FOA	biospider
Furan-2-carbonsaeure	ChEBI
Furan-2-carboxylic acid	biospider
Furancarboxylate	biospider
Furancarboxylic acid	biospider
Furancarboxylic acid-(2)	biospider
Furoate	biospider
Furoic acid	biospider
Furoica	biospider
Pyromucate	biospider
Pyromucic acid	db_source
α-furancarboxylate	Generator
α-furancarboxylic acid	Generator
α-furoate	Generator
α-furoic acid	Generator

Chemical Formula

C5H4O3

IUPAC name

furan-2-carboxylic acid

InChI Identifier

InChI=1S/C5H4O3/c6-5(7)4-2-1-3-8-4/h1-3H,(H,6,7)

InChI Key

SMNDYUVBFMFKNZ-UHFFFAOYSA-N

Isomeric SMILES

OC(=O)C1=CC=CO1

Average Molecular Weight

112.0835

Monoisotopic Molecular Weight

112.016043994

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as furoic acids. These are organic compounds containing a furoic acid moiety, with a structure characterized by a furan ring bearing a carboxylic acid group at the C2 or C3 carbon atom.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Furans

Sub Class

Furoic acid and derivatives

Direct Parent

Furoic acids

Alternative Parents