Record Information
Version1.0
Creation date2015-10-09 22:30:55 UTC
Update date2017-01-19 02:36:25 UTC
FoodComEx IDPC000491
FoodDB RecordFDB022708
Chemical Information
NameVerapamil
DescriptionA calcium channel blocker that is a class IV anti-arrhythmia agent. -- Pubchem; Calcium channel antagonists can be quite toxic. In the management of poisoning, early recognition is critical. Calcium channel antagonists are frequently prescribed, and the potential for serious morbidity and mortality with over dosage is significant. Ingestion of these agents should be suspected in any patient who presents in an overdose situation with unexplained hypotension and conduction abnormalities. The potential for toxicity should be noted in patients with underlying hepatic or renal dysfunction who are receiving therapeutic doses. (PMID 8213877) [HMDB]
CAS Number52-53-9
Structure
Thumb
Synonyms
SynonymSource
Akilenhmdb
Anpechmdb
Apo-Veraphmdb
Arpamyl LPhmdb
Berkatenshmdb
Calanhmdb
Calan SRhmdb
Calaptinhmdb
Calaptin 240 SRhmdb
Calcanhmdb
Cardiabeltinhmdb
Cardiagutthmdb
Cardibeltinhmdb
Cardioprotecthmdb
Caverilhmdb
Civicorhmdb
Civicor Retardhmdb
Coraverhmdb
Cordiloxhmdb
Cordilox SRhmdb
Corpamilhmdb
Covera-Hshmdb
D-365hmdb
delta-365hmdb
Dignoverhmdb
Dilacoranhmdb
Dilacoran HTAhmdb
Durasoptinhmdb
Elthonhmdb
Falicardhmdb
Finoptinhmdb
Flamonhmdb
Geanginhmdb
Hartezehmdb
Hexasoptinhmdb
Hexasoptin Retardhmdb
Hormitolhmdb
Ikacorhmdb
Ikapresshmdb
Inselonhmdb
Iproveratrilhmdb
Isoptinhmdb
Isoptin Retardhmdb
Isoptin SRhmdb
Isoptinehmdb
Isoptinohmdb
Isotopinhmdb
Izoptinhmdb
Jenapamilhmdb
Lekoptinhmdb
Lodixalhmdb
Magotironhmdb
Manidonhmdb
Manidon Retardhmdb
Novapamyl LPhmdb
Novo-Veramilhmdb
Nu-Veraphmdb
Ormilhmdb
Praecicorhmdb
Quasarhmdb
Rapamhmdb
Robatelanhmdb
Securonhmdb
Tarkahmdb
Univerhmdb
Univexhmdb
Vasolanhmdb
Vasomilhmdb
Vasoptenhmdb
Vera-Sanoraniahmdb
Verabetahmdb
Veracaps SRhmdb
Veracorhmdb
Verahexalhmdb
Veralochmdb
Veramexhmdb
Veramilhmdb
Verapamilhmdb
Verapamil Acishmdb
Verapamil ALhmdb
Verapamil Atidhmdb
Verapamil Basicshmdb
Verapamil Ebewehmdb
Verapamil hclHMDB
Verapamil Henninghmdb
Verapamil Injectionhmdb
Verapamil MSDhmdb
Verapamil NMhmdb
Verapamil NM Pharmahmdb
Verapamil Nordichmdb
Verapamil PBhmdb
Verapamil Rikerhmdb
Verapamil SRhmdb
Verapamil Verlahmdb
Verapamil-AbZhmdb
VerapamiloHMDB
VerapamilumHMDB
Verapinhmdb
Verapress 240 SRhmdb
Verasalhmdb
Verasifarhmdb
Veratensinhmdb
Verdilachmdb
Verelanhmdb
Verelan PMhmdb
Verelan SRhmdb
Veroptinstadahmdb
Verpamilhmdb
Vetrimilhmdb
Vortachmdb
Chemical FormulaC27H38N2O4
IUPAC name2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
InChI IdentifierInChI=1S/C27H38N2O4/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6/h9-12,17-18,20H,8,13-16H2,1-7H3
InChI KeySGTNSNPWRIOYBX-UHFFFAOYSA-N
Isomeric SMILESCOC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
Average Molecular Weight454.6016
Monoisotopic Molecular Weight454.283157714
Chemical Taxonomy
Description Belongs to the class of organic compounds known as phenylbutylamines. Phenylbutylamines are compounds containing a phenylbutylamine moiety, which consists of a phenyl group substituted at the fourth carbon by an butan-1-amine.
KingdomOrganic compounds
Super ClassBenzenoids
ClassBenzene and substituted derivatives
Sub ClassPhenylbutylamines
Direct ParentPhenylbutylamines
Alternative Parents
Substituents
  • Phenylbutylamine
  • Dimethoxybenzene
  • O-dimethoxybenzene
  • Phenethylamine
  • Phenylpropane
  • Anisole
  • Phenol ether
  • Phenoxy compound
  • Methoxybenzene
  • Alkyl aryl ether
  • Aralkylamine
  • Tertiary aliphatic amine
  • Tertiary amine
  • Nitrile
  • Carbonitrile
  • Ether
  • Organic oxygen compound
  • Amine
  • Organic nitrogen compound
  • Organooxygen compound
  • Organonitrogen compound
  • Organopnictogen compound
  • Hydrocarbon derivative
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logPNot Available
Experimental Water SolubilityNot Available
Melting PointNot Available
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 200 mg
Delivery TimeNot Available
Storage Formsolid
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
AKSci 9874AJ