FComEx: Thymine 2-desoxyriboside (PC000138)

Record Information

Version

1.0

Creation date

2015-10-09 22:28:47 UTC

Update date

2017-01-19 02:36:14 UTC

FoodComEx ID

PC000138

FoodDB Record

FDB012757

Chemical Information

Name

Thymine 2-desoxyriboside

Description

Isolated from seedlings of Phaseolus vulgaris (kidney bean) Deoxythymidine is non-toxic and as part of one of the four nucleotides in DNA it is a naturally occurring compound that exists in all living organisms and DNA viruses. RNA has uridine (uracil joined to ribose) instead. Uracil is chemically very similar to thymine, the latter being 5-methyluracil. Since thymine nucleotides are precursors of DNA, not RNA, the prefix "deoxy" is often left out, i.e., deoxythymidine is often just called thymidine.; In its composition, deoxythymidine is a nucleoside composed of deoxyribose (a pentose sugar) joined to the pyrimidine base thymine.; Iododeoxyuridine is a radiosensitizer and increases the amount of DNA damage received from ionizing radiation.; Thymidine (more precisely called deoxythymidine; can also be labelled deoxyribosylthymine, and thymine deoxyriboside) is a chemical compound, more precisely a pyrimidine deoxynucleoside. Deoxythymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in S phase.; Thymidine is non-toxic and is a naturally occurring compound that exists in all living organisms and DNA viruses. 25% of DNA is composed of thymidine. RNA does not have thymidine and has uridine instead. Thymidine is a chemical compound which is a pyrimidine nucleoside. Thymidine is the DNA base T, which pairs with adenosine in double stranded DNA. Thymine 2-desoxyriboside is found in pulses, yellow wax bean, and green bean.

CAS Number

50-89-5

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
(3H)Thymidine	biospider
β-D-Ribofuranoside, thymine-1 2-deoxy-	biospider
1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione	HMDB
1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione, 9CI	db_source
1-(2-Deoxy-b-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione	Generator
1-(2-Deoxy-b-D-ribofuranosyl)-5-methyluracil	db_source
1-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione	ChEBI
1-(2-Deoxy-beta-D-ribofuranosyl)-5-methyluracil	biospider
1-(2-Deoxy-beta-D-ribofuranosyl)thymine	biospider
1-(2-Deoxy-beta-delta-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione	HMDB
1-(2-Deoxy-beta-ribofuranosyl)-5-methyluracil	biospider
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione	Generator
1-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione	HMDB
2-deoxythymidine	biospider
2-Desoxy-thymidine	biospider
2'-deoxy-5-methyl-Uridine	biospider
2'-deoxy-5-methyluridine	biospider
2'-Deoxythymidine	biospider
2'-thymidine	biospider
5-Methyl-2'-deoxyuridine	biospider
5-Methyldeoxyuridine	biospider
5-Methyldeoxyurindine	biospider
beta-D-Ribofuranoside, thymine-1 2-deoxy-	biospider
Deoxyribothymidine	biospider
Deoxythymidin	biospider
Deoxythymidine	biospider
Desoxy-thymidin	biospider
DT	biospider
DTHD	biospider
Dthyd	biospider
NSC 21548	db_source
THM	biospider
Thymidin	biospider
Thymidine	ChEBI
Thymidine (8CI,9CI)	biospider
Thymidine-(H-3)	biospider
Thymidine, 2'-deoxy-	biospider
Thymidine, labeled with tritium	biospider
Thymine 2-desoxyriboside	db_source
thymine 2'-deoxyriboside	biospider
Thymine deoxyriboside	biospider
thymine-1 2-deoxy-b-D-Ribofuranoside	biospider
thymine-1 2-deoxy-beta-delta-Ribofuranoside	biospider
Thymine-2-deoxyriboside	biospider
Thymine-2-desoxyriboside	biospider
Thyminedeoxyriboside	biospider
Thymosine	db_source
Tritiated thymidine	biospider
Uridine, 2'-deoxy-5-methyl-	biospider

Chemical Formula

C10H14N2O5

IUPAC name

4-hydroxy-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2-dihydropyrimidin-2-one

InChI Identifier

InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)

InChI Key

IQFYYKKMVGJFEH-UHFFFAOYSA-N

Isomeric SMILES

CC1=CN(C2CC(O)C(CO)O2)C(=O)N=C1O

Average Molecular Weight

242.2286

Monoisotopic Molecular Weight

242.090271568

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleosides. Pyrimidine 2'-deoxyribonucleosides are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2.

Kingdom

Organic compounds

Super Class

Nucleosides, nucleotides, and analogues

Class

Pyrimidine nucleosides

Sub Class

Pyrimidine 2'-deoxyribonucleosides

Direct Parent

Pyrimidine 2'-deoxyribonucleosides

Alternative Parents