Record Information
Version1.0
Creation date2015-10-09 22:28:06 UTC
Update date2017-01-19 02:36:12 UTC
FoodComEx IDPC000084
FoodDB RecordFDB012567
Chemical Information
NameL-Aspartic acid
DescriptionAspartic acid (Asp, D), also known as aspartate, the name of its anion, is one of the 20 natural proteinogenic amino acids which are the building blocks of proteins. As its name indicates, aspartic acid is the carboxylic acid analog of asparagine. As a neurotransmitter, aspartic acid may provide resistance to fatigue and thus lead to endurance, although the evidence to support this idea is not strong. Aspartic acid is a nonessential amino acid, since it can be made from glutamic acid by enzymes using vitamin B6. The amino acid has important roles in the urea cycle and DNA metabolism. Aspartic acid is a major excitatory neurotransmitter, which is sometimes found to be increased in epileptic and stroke patients. It is decreased in depressed patients and in patients with brain atrophy. Aspartic acid supplements are being evaluated. Five grams can raise blood levels. Magnesium and zinc may be natural inhibitors of some of the actions of aspartic acid. Aspartic acid, with the amino acid phenylalanine, is a part of the natural sweetener, aspartame. This sweetener is an advance in artificial sweeteners and is probably safe in normal doses to all except phenylketonurics. The jury is still out on the long-term effects it has on many brain neurohormones. Aspartic acid may be a significant immunostimulant of the thymus and can protect against some of the damaging effects of radiation. Many claims have been made for the special value of administering aspartic acid in the form of potassium and magnesium salts. Since aspartic acid is relatively nontoxic, studies are now in progress to elucidate its pharmacological and therapeutic roles.
CAS Number56-84-8
Structure
Thumb
Synonyms
SynonymSource
(+)-Aspartatebiospider
(+)-Aspartic acidbiospider
(2S)-2-Aminobutanedioic acidbiospider
(2S)-Aspartatebiospider
(2S)-Aspartic acidbiospider
(L)-Aspartatebiospider
(L)-Aspartic acidbiospider
(R)-2-AminosuccinateHMDB
(S)-(+)-Aminosuccinic acidbiospider
(S)-(+)-Aspartatebiospider
(S)-(+)-Aspartic acidbiospider
(S)-2-AminobutanedioateGenerator
(S)-2-Aminobutanedioic acidbiospider
(S)-2-Aminosuccinatebiospider
(S)-2-Aminosuccinic acidbiospider
(S)-amino-ButanedioateHMDB
(S)-amino-Butanedioic acidHMDB
(S)-Aminobutanedioatebiospider
(S)-Aminobutanedioic acidbiospider
(S)-Aspartatebiospider
(S)-Aspartic acidbiospider
2-amino-3-MethylsuccinateHMDB
2-amino-3-Methylsuccinic acidHMDB
2-AminosuccinateGenerator
2-Aminosuccinic acidChEBI
alpha-AminosuccinateHMDB
alpha-Aminosuccinic acidHMDB
AminosuccinateHMDB
AspChEBI
AsparagateHMDB
Asparagic acidHMDB
AsparaginateHMDB
Asparaginic acidHMDB
AsparatateHMDB
ASPARTateGenerator
Aspartic acid, INN, USAN; L-formdb_source
Aspartic acid, L- (8CI)biospider
DChEBI
FEMA 3656db_source
H-Asp-OHHMDB
L-(+)-Aspartatebiospider
L-(+)-Aspartic acidbiospider
L-2-Aminobutanedioic acidbiospider
L-Aminosuccinatebiospider
L-Aminosuccinic acidbiospider
L-Asparagatebiospider
L-Asparagic acidbiospider
L-Asparaginatebiospider
L-Asparaginic acidbiospider
L-AsparaginsaeureChEBI
L-Aspartatebiospider
L-Aspartic acid (9CI)biospider
Chemical FormulaC4H7NO4
IUPAC name(2S)-2-aminobutanedioic acid
InChI IdentifierInChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI KeyCKLJMWTZIZZHCS-REOHCLBHSA-N
Isomeric SMILESN[C@@H](CC(O)=O)C(O)=O
Average Molecular Weight133.1027
Monoisotopic Molecular Weight133.037507717
Chemical Taxonomy
ClassificationNot classified
Physico-Chemical Properties - Experimental
PropertyValueReference
Experimental logP-3.89CHMELIK,J ET AL. (1991)
Experimental Water Solubility5.36 mg/mL at 25 oCYALKOWSKY,SH & HE,Y (2003)
Melting PointMp 269-271° dec.DFC
Foods of Origin
FoodContent Range AverageReference
FoodReference
Production Data
Production Methodcommercial
Production Method ReferenceNot Available
Production Method Reference FileNot Available
Quantity AvailableProduction upon request, up to 7 g
Delivery TimeNot Available
Storage Formsolid
Storage Conditions-80°C
StabilityNot Available
PurityNot Available
Spectra
Spectral Data Upon RequestNot Available
Provider Information
Contact NameContact InstitutionContact Email
Rosa Vazquez Fresnovazquezf@ualberta.ca
Commercial Vendors
AKSci G144
Alfa Aesar HMDB0000191
Glentham GM3196
Glentham GM0348
MetaSci HMDB0000191
Toronto Research Chemicals A790024