FComEx: Nicotinamide (PC000070)

Record Information

Version

1.0

Creation date

2015-10-09 22:27:57 UTC

Update date

2017-01-19 02:36:11 UTC

FoodComEx ID

PC000070

FoodDB Record

FDB012485

Chemical Information

Name

Nicotinamide

Description

Niacinamide, also known as nicotinamid or nicovit, belongs to the class of organic compounds known as nicotinamides. These are heterocyclic aromatic compounds containing a pyridine ring substituted at position 3 by a carboxamide group. Niacinamide is a strong basic compound (based on its pKa). Niacinamide exists in all living species, ranging from bacteria to humans. niacinamide and phosphoribosyl pyrophosphate can be converted into nicotinic acid mononucleotide and phosphate through the action of the enzyme nicotinamide phosphoribosyltransferase. In humans, niacinamide is involved in the metabolic disorder called the nad+ signalling pathway (cancer). Niacinamide is an odorless tasting compound. Outside of the human body, Niacinamide is found, on average, in the highest concentration within a few different foods, such as common sages, milk (cow), and cocoa beans and in a lower concentration in common pea and beers. Niacinamide has also been detected, but not quantified in, several different foods, such as pineappple sages, boysenberries, cashew nuts, macadamia nut (m. tetraphylla), and sweet marjorams. This could make niacinamide a potential biomarker for the consumption of these foods. Niacinamide is a potentially toxic compound. A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.

CAS Number

98-92-0

Structure

MOL SDF PDB SMILES InChI

Synonyms

Synonym	Source
β-Pyridinecarboxamide	biospider
3-(Aminocarbonyl)pyridine	biospider
3-Amidopyridine	biospider
3-Carbamoylpyridine	biospider
3-Pyridinecarboxamide	biospider
3-Pyridinecarboxylic acid amide	biospider
6-Aminonicotinamide	biospider
Acid amide	HMDB
Amid kyseliny nikotinove	HMDB
Amide PP	biospider
Aminicotin	HMDB
Amixicotyn	HMDB
Amnicotin	HMDB
Austrovit PP	HMDB
b-Pyridinecarboxamide	biospider
Benicot	manual
beta-Pyridinecarboxamide	biospider
Delonin amide	manual
Dipegyl	HMDB
Dipigyl	HMDB
Endobion	HMDB
Factor PP	HMDB
Hansamid	HMDB
Inovitan PP	HMDB
m-(Aminocarbonyl)pyridine	biospider
Mediatric	HMDB
NAM	HMDB
Nandervit-N	HMDB
Niacevit	HMDB
Niacinamide	db_source
Niamide	HMDB
Niavit PP	HMDB
Nicamide	HMDB
Nicamina	HMDB
Nicamindon	HMDB
Nicasir	HMDB
Nicobion	HMDB
Nicofort	HMDB
Nicogen	HMDB
Nicomidol	HMDB
Nicosan 2	HMDB
Nicosylamide	manual
Nicota	HMDB
Nicotamide	biospider
Nicotilamide	biospider
Nicotililamido	HMDB
Nicotinamid	ChEBI
Nicotinamida	HMDB
Nicotinamide	biospider
Nicotinamidum	HMDB
Nicotinate amide	Generator
Nicotine acid amide	biospider
Nicotine amide	biospider
Nicotinic acid amide	db_source
Nicotinic amide	biospider
Nicotinsaeureamid	ChEBI
Nicotinsaureamid	HMDB
Nicotol	HMDB
Nicotylamide	biospider
Nicotylamidum	HMDB
Nicovel	HMDB
Nicovit	HMDB
Nicovitina	HMDB
Nicovitol	HMDB
Nicozymin	HMDB
Nictoamide	HMDB
Niko-tamin	HMDB
Nikotinamid	ChEBI
Nikotinsaeureamid	ChEBI
Niocinamide	HMDB
Niozymin	HMDB
Papulex	HMDB
Pelmin	HMDB
Pelmine	HMDB
Pelonin amide	HMDB
PP-Faktor	HMDB
Pyridine-3-carboxylic acid amide	biospider
Savacotyl	HMDB
Vi-nicotyl	HMDB
Vi-noctyl	HMDB
Vitamin B3 (Nicotinamide)	biospider
Vitamin PP	ChEBI
Vitamin PP (Nicotinamide)	biospider
Witamina PP	HMDB
β-pyridinecarboxamide	Generator

Chemical Formula

C6H6N2O

IUPAC name

pyridine-3-carboxamide

InChI Identifier

InChI=1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI Key

DFPAKSUCGFBDDF-UHFFFAOYSA-N

Isomeric SMILES

NC(=O)C1=CC=CN=C1

Average Molecular Weight

122.1246

Monoisotopic Molecular Weight

122.048012824

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as nicotinamides. These are heterocyclic aromatic compounds containing a pyridine ring substituted at position 3 by a carboxamide group.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Pyridines and derivatives

Sub Class

Pyridinecarboxylic acids and derivatives

Direct Parent

Nicotinamides

Alternative Parents