Provider Information
Registered on2018-04-25 10:07:14 UTC
First NameThierry
Last NameDurand
E-mailthierry.durand@umontpellier.fr
GenderMale
PositionResearcher
InstitutionInstitut des Biomol├ęcules Max Mousseron (IBMM), UMR 247, CNRS, UM, ENSCM
Institution TypeResearch Institute
AddressInstitut des Biomol├ęcules Max Mousseron (IBMM), UMR 247, CNRS, UM, ENSCM
CityMontpellier
CountryFR
Zip Code34093
Phone Number0411759558
Research Information
General Area of ResearchOrganic Synthesis, lipidomics, biomarkers
Detailed Area of ResearchResearch in my group has focused on total synthesis of oxygenated metabolites cyclic and non cyclic of omega 6 and omega 3 polyunsaturated fatty acids (PUFAs) for over 25 years. Recently we were engaged on synthesis of lipophenols, lipopeptides and on developing GC-MS and LC-MS methodologies to quantify these isoprostanoids. We were the first to describe the total synthesis of series of isoprostanes, neuroprostanes and phytoprostanes as well as dihomo-isofurans, neurofurans and phytofurans. We collaborate with a number of teams all around the word in the field of all these biomolecules and related analogs linked to nutrition health (pain, cardiovascular, neurodegenerative diseases) and recently in the field of agrochemistry with the non enzymatic oxygenated metabolites (phytoprostanes/phytofurans) derived from alpha-linolenic acid (ALA, C18:3 n-3).
Activities
  • Chemical synthesis of food compounds or metabolites
  • Metabolism of food compounds in vivo (human/animal models/cell culture)
  • Analytics
    • Food compounds
    • NMR
    • LC-MS
    • GC-MS
Interests
  • Offering pure compounds or their metabolites
Purpose of Use
  • Identification of markers from nutrimetabolomics studies
  • Investigation of biological effects of food components or their metabolites